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Dolutegravir intermediate-1

CAS No. 1335210-23-5

Dolutegravir intermediate-1( 1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid | 1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid )

Catalog No. M23489 CAS No. 1335210-23-5

Dolutegravir intermediate-1 is a new synthetic Dolutegravir intermediate extracted from patent WO 2016125192 A2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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500MG 52 In Stock
1G 67 In Stock
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Biological Information

  • Product Name
    Dolutegravir intermediate-1
  • Note
    Research use only, not for human use.
  • Brief Description
    Dolutegravir intermediate-1 is a new synthetic Dolutegravir intermediate extracted from patent WO 2016125192 A2.
  • Description
    Dolutegravir intermediate-1 is a new synthetic Dolutegravir intermediate extracted from patent WO 2016125192 A2. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-1 infection.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid | 1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV-1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1335210-23-5
  • Formula Weight
    314.27
  • Molecular Formula
    C13H16NO8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 100 mg/mL (285.46 mM; Need ultrasonic)
  • SMILES
    COC(CN(C=C(C([O-])=O)C1=O)C(C(OC)=O)=C1OC)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sivaram Prasad, et al. Process for the preparation of dolutegravir . WO 2016125192 A2.
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